直到Vosoritide的获批，才让ACH治疗迈入一个全新的靶向治疗时代。它是一种C型利钠肽(CNP)类似物，通过结合NPR-B进而降低FGFR3的活性来促进生长。临床结果试验显示：相较于安慰剂，每日皮下注射15 μg/kg的Vosoritide，受试者平均年身高增加了1.57厘米。
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requirements often included additional card punches and readers for data entry,
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The tradeoff is complexity. The microcode must be carefully arranged so that the instructions in delay slots are either useful setup for both paths, or at least harmless if the redirect fires. Not every case is as clean as RETF. When a PLA redirect interrupts an LCALL, the return address is already pushed onto the microcode call stack (yes, the 386 has a microcode call stack) -- the redirected code must account for this stale entry. When multiple protection tests overlap, or when a redirect fires during a delay slot of another jump, the control flow becomes hard to reason about. During the FPGA core implementation, protection delay slot interactions were consistently the most difficult bugs to track down.